Evaluation and management of Giant Cell Tumor of the Distal Fibula, a Case Report
Keywords:
Giant cell tumor, Distal fibula, Tibiotalus fusion, Ankle function, Case reportAbstract
BACKGROUND
It is rare for giant cell tumor to occur in the distal fibula and there is no consensus on the modality of management of such tumor
CASE SUMMARY
A 48 -old woman who had a long-standing history of pain and swelling of the right lateral malleolus presented to our hospital.
imaging revealed a 7 cm x4 cm cystic expansile lytic lesion occupying the lateral malleolus.
The biopsy obtained by excising the mass confirmed it was a giant cell tumor. The patient was a known case of End Stage Renal Disease, after consulting anesthesia regarding patient preparation for surgery and considering treatment options with the patient we proceeded to preform excision of the mass and tibiotalar fusion, which performed well in the 6-month period of follow up with the patient
CONCLUSION
Tumor resection of the distal fibula and tibiotalar fusion of the ankle is a successful option for the management of such case
References
Montgomery C, Couch C, Emory CL, Nicholas R. Giant Cell Tumor of Bone: Review of Current Literature, Evaluation, and Treatment Options. J Knee Surg. 2019;32:331–336. doi: 10.1055/s-0038-1675815. [DOI] [PubMed] [Google Scholar].
Werner M. Giant cell tumour of bone: morphological, biological and histogenetical aspects. Int Orthop. 2006;30:484–489. doi: 10.1007/s00264-006-0215-7. [DOI] [PMC free article] [PubMed] [Google Scholar]
Chan CM, Adler Z, Reith JD, Gibbs CP Jr. Risk factors for pulmonary metastases from giant cell tumor of bone. J Bone Joint Surg Am. 2015;97:420–428. doi: 10.2106/JBJS.N.00678. [DOI] [PubMed] [Google Scholar]
Rosario M, Kim HS, Yun JY, Han I. Surveillance for lung metastasis from giant cell tumor of bone. J Surg Oncol. 2017;116:907–913. doi: 10.1002/jso.24739. [DOI] [PubMed] [Google Scholar]
Parmeggiani A, Miceli M, Errani C, Facchini G. State of the Art and New Concepts in Giant Cell Tumor of Bone: Imaging Features and Tumor Characteristics. Cancers (Basel) 2021;13 doi: 10.3390/cancers13246298. [DOI] [PMC free article] [PubMed] [Google Scholar]
Aiyer AA, Zachwieja EC, Lawrie CM, Kaplan JRM. Management of Isolated Lateral Malleolus Fractures. J Am Acad Orthop Surg. 2019;27:50–59. doi: 10.5435/JAAOS-D-17-00417. [DOI] [PubMed] [Google Scholar]
Wang J, Du Z, Yang R, Tang X, Guo W. Lateral malleolus en bloc resection for the distal fibula osteosarcoma based on a new classification and proposed reconstruction choice: Analysis of 6 cases prognosis and literature review. Foot Ankle Surg. 2020;26:855–863. doi: 10.1016/j.fas.2019.11.003. [DOI] [PubMed] [Google Scholar]
Vaishya R, Kapoor C, Golwala P, Agarwal AK, Vijay V. A Rare Giant Cell Tumor of the Distal Fibula and its Management. Cureus. 2016;8:e666. doi: 10.7759/cureus.666. [DOI] [PMC free article] [PubMed] [Google Scholar]
Bhowmick K, Boopalan PRJVC. Saving the ankle in distal fibular giant cell tumour - A case report. J Clin Orthop Trauma. 2019;10:1054–1058. doi: 10.1016/j.jcot.2019.03.010. [DOI] [PMC free article] [PubMed] [Google Scholar]
Bukata SV, Blay JY, Rutkowski P, Skubitz K, Henshaw R, Seeger L, Dai T, Jandial D, Chawla S. Denosumab Treatment for Giant Cell Tumor of the Spine Including the Sacrum. Spine (Phila Pa 1976) 2021;46:277–284. doi: 10.1097/BRS.0000000000003728. [DOI] [PMC free article] [PubMed] [Google Scholar]
Capanna R, van Horn JR, Biagini R, Ruggieri P, Bettelli G, Campanacci M. Reconstruction after resection of the distal fibula for bone tumor. Acta Orthop Scand. 1986;57:290–294. doi: 10.3109/17453678608994394. [DOI] [PubMed] [Google Scholar]
Ring A, Kirchhoff P, Goertz O, Behr B, Daigeler A, Lehnhardt M, Harati K. Reconstruction of Soft-Tissue Defects at the Foot and Ankle after Oncological Resection. Front Surg. 2016;3:15. doi: 10.3389/fsurg.2016.00015. [DOI] [PMC free article] [PubMed] [Google Scholar]
Vidal L, Kampleitner C, Brennan MÁ, Hoornaert A, Layrolle P. Reconstruction of Large Skeletal Defects: Current Clinical Therapeutic Strategies and Future Directions Using 3D Printing. Front Bioeng Biotechnol. 2020;8:61. doi: 10.3389/fbioe.2020.00061. [DOI] [PMC free article] [PubMed] [Google Scholar]
Kundu ZS, Gogna P, Gupta V, Singla R, Sangwan SS, Mohindra M, Singh A. Ankle fusion with centralisation of the fibula after distal tibia bone tumour resection. J Orthop Traumatol. 2014;15:95–101. doi: 10.1007/s10195-013-0279-2. [DOI] [PMC free article] [PubMed] [Google Scholar]
Asomugha EU, Den Hartog BD, Junko JT, Alexander IJ. Tibiotalocalcaneal Fusion for Severe Deformity and Bone Loss. J Am Acad Orthop Surg. 2016;24:125–134. doi: 10.5435/JAAOS-D-14-00102. [DOI] [PubMed] [Google Scholar]
Hanna M, Whicker EA, Traub B, Allam E, Labib SA. Sport activity levels following ankle fusion. Int Orthop. 2021;45:2347–2354. doi: 10.1007/s00264-021-05100-7. [DOI] [PubMed] [Google Scholar]
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2025 Y Elghawail، M Alsaqaier ، N Bouzgayya
This work is licensed under a Creative Commons Attribution 4.0 International License.
