مجلة البحوث الأكاديمية

Multiple spinal and cranial meningiomas

2025-01-29T11:01:39+00:00

Though meningiomas are common neoplasms of the nervous system, the occurrence of multiple meningiomas in different neuraxial compartments is rather rare. We report a case of A 28-years old girl presented to neurosurgery outpatient clinic of National Cancer Institute, Misurata - Libya complaining of headache, increased attacks of convulsions (she has been on anti-convulsant since childhood , valproic acid ) and unsteadiness. She walks with assistance and has a history of bowel and bladder dysfunction and right eye visual loss. Her Cranial and spinal magnetic resonance imaging (MRI) revealed multiple homogenously enhancing lesions in the left parieto-temporal region ,craniometrical junction, lumbar and sacral regions..

She underwent multiple surgeries including left side frontotemporal craniotomy, suboccipital craniotomy and spinal laminectomy in different sessions and total removal of thd tumors was achieved.

Only about 19 cases of multiple cranial and spinal meningiomas have been reported, of which, only five cases have more than one spinal meningioma. The implication of the incidence of such multiple meningiomas in the same patient with relevance to investigations and decision making are discussed along with a brief review of literature of cases with multiple spinal and cranial meningiomas.

Evaluation and management of Giant Cell Tumor of the Distal Fibula, a Case Report

2025-02-02T09:44:07+00:00

BACKGROUND

It is rare for giant cell tumor to occur in the distal fibula and there is no consensus on the modality of management of such tumor

CASE SUMMARY

A 48 -old woman who had a long-standing history of pain and swelling of the right lateral malleolus presented to our hospital.

imaging revealed a 7 cm x4 cm cystic expansile lytic lesion occupying the lateral malleolus.

The biopsy obtained by excising the mass confirmed it was a giant cell tumor. The patient was a known case of End Stage Renal Disease, after consulting anesthesia regarding patient preparation for surgery and considering treatment options with the patient we proceeded to preform excision of the mass and tibiotalar fusion, which performed well in the 6-month period of follow up with the patient

CONCLUSION

Tumor resection of the distal fibula and tibiotalar fusion of the ankle is a successful option for the management of such case

The possibility of preparing solid Co-crystals forms of sulfamethoxazole-trimethoprim (SMZ-TMP)

2025-01-29T10:45:44+00:00

This study explores the preparation and characterization of solid co-crystals of sulfamethoxazole (SMZ) and trimethoprim (TMP) to enhance their pharmaceutical properties, particularly solubility and stability. SMZ-TMP co-crystals were successfully obtained using methanol, while a salt form emerged in tetrahydrofuran (THF), demonstrating solvent-dependent behavior. Various characterization techniques, including Differential Scanning Calorimetry (DSC), Fourier Transform Infrared Spectroscopy (FTIR), and Powder X-ray Diffraction (PXRD), were employed to confirm the formation and properties of the co-crystals. The SMZ-TMP co-crystal exhibited improved thermal stability and distinct molecular interactions, as evidenced by changes in FTIR hydrogen-bonding regions and thermal analysis.

Enhanced Lipofilling Outcomes Using Platelet-Rich Plasma: An Innovative Approach

2025-02-02T09:31:41+00:00

Introduction:

Adipose tissue for autotransplantation is easily accessible. Due to comparatively variable and unexpected survival, the popularity of fat transfer surgery has fluctuated throughout the years. The outcome of autologous fat tissue grafts is influenced by numerous factors, some of which the surgeon can manage, like Aseptic procedures, low pressure suction, cautious handling of graft tissues, and the use of minimally traumatic cannulae. There is growing evidence that careful donor site selection and manipulation of specific healing mechanisms that regulate cellular recruitment, migration, and differentiation at the recipient site may improve the consistency and dependability of fat grafts.

The purpose of this paper to investigate the improving the survivability and outcome of using transplanted fat with PRP as an alternative to soft tissue augmentation using only fat tissue transfer as the ordinary procedure

Materials and Methods:

The study here is a preliminary clinical investigation combined with a description of a novel technique. It introduces a new method of enhancing autologous fat transplantation with platelet-rich plasma (PRP) and reports initial clinical observations.

Results: A higher percentage of graft volume retention (about 91% of the volume of the transferred tissue after 6months post-surgery) appears to be produced following the use of these procedures with all the patients, and regarding to the complication, I observe that The percentage of secondary calcifications occurred in 4% of the patients, and microcyst formation was observed in 3% of them.

A study on dental cleaning methods And the extent of its impact on bacterial plaque (dental)

2025-01-29T10:28:28+00:00

This study was experimented to determine whether the dental cleaning methods used in the community were correct or not, and to determine the extent of the impact of these methods on the formation of bacterial plaque (dental), as well as the methods of cleaning and identifying bacterial plaque, tooth decay, and oral and dental care methods, and the study was conducted during the period During the period (12) 2016 until the end of the month (6) 2017 on a random sample that includes 50 people (25 male students, 25 female students), a clinical examination was conducted inside the dental clinic at the College of Medical Technology - Misurata, during the period from month (2) to month (3).

The data that were recorded and analyzed in this study were obtained from the clinical detection of the Dental Plaque Index (D.P.I) in the mouth.

Research about the association between smartphone use and carpal tunnel syndrome research

2025-02-02T09:16:37+00:00

Carpal tunnel syndrome (CTS) is the most common upper extremity nerve compression syndrome Which affect the median nerve.

Patients with CTS experience reduced sensation, dexterity, and function.

Irreversible changes in nerve structure and function due to demyelination and axonal damage can occur in long-standing case.

Retrospective Analysis of Inguinal Hernia in Pediatric Patients in a Tertiary Center, Misurata– Libya

2025-01-29T11:21:18+00:00

Background: Inguinal hernia repair is one of the most commonly performed operations and it is among the most frequent reasons for referral to pediatric surgery clinics. The incidence of inguinal hernia is 1-5% in the pediatric population and is even higher in premature babies, as high as 10-30%.

Aim of the study: to analyze inguinal hernia distribution according to age, gender, side and associated congenital anomalies in the pediatric population.

Materials and Methods: A descriptive retrospective study included all pediatric patients diagnosed as inguinal hernia and operated at pediatric surgery department in Misurata Medical Center during the year of 2022. Hospital records were reviewed, and patients' data were collected in terms of age, sex, site of hernia, presence of incarceration and congenital abnormality association.

Results: 103 patients included in the study, 77 (74.8%) patients were males and 26 (25.2%) were females, with a female to male ratio 1:2.96. Age of patients ranged from 1 month to 14 years, with mean age of 2.9 years. Right side was affected in 51 patients (49.5%), while left side was 37 patients (35.9%), bilateral inguinal hernia was found in 15 patients (14.6%). Elective cases were 99 patients (96.1%), while urgent cases were 4 patients (3.9%) with diagnosis of incarcerated or strangulated hernia. 98 (95.1%) cases did not have any association, while associated conditions were undescended testis, hydrocele and umbilical hernia.

Core Decompression as Treatment in Avascular Necrosis of the Femoral Head

2025-02-02T09:51:52+00:00

Core decompression is a minimally invasive surgical procedure commonly used to treat avascular necrosis (AVN) of the femoral head, a condition caused by disrupted blood supply leading to bone death and eventual joint collapse. The procedure involves drilling one or more small channels into the necrotic bone to relieve intraosseous pressure, enhance vascularization, and stimulate the formation of new bone tissue. Core decompression is most effective in the early stages of AVN (Ficat stages I and II), where joint collapse has not occurred.

Clinical outcomes :

suggest significant pain relief and improved function in patients with early-stage AVN. When combined with adjunct therapies, such as bone grafts, stem cells, or biologics, the success rate improves further. While it is generally considered safe,

complications :

such as fractures are possible. This review highlights the indications, technique, efficacy, and potential complications of core decompression for AVN of the femoral head.

Surgical management of Benign Prostatic Hyperplasia: Transvesical prostatectomy versus Transurethral resection of prostate with a volume range of 70–100 gram

2025-01-29T10:56:32+00:00

Objectives: This study aims to compare the short-term outcomes and complications of transvesical prostatectomy versus monopolar transurethral resection of the prostate between 70 and 100 grams.

Methods and material: This is a retrospective descriptive study conducted from April 2017 to April 2021. A total of 59 patients were admitted and underwent transvesical prostatectomy (TVP) and transurethral resection of the prostate (TURP) at Misrata Medical Center (department of urology). Patients with prostatic volume between 70-100 g were included in this study, while patients with prostatic volume greater than 100 g or less than 70 g were excluded. Types of surgery (TVP and TURP), patient age, size of the prostate gland, duration of surgery (mins), blood transfusion, clot retention, length of catheterization (days), hospital stay (days), post-operative infection, incontinence, reoperation, bladder neck stenosis, and urethral stricture were analyzed.

Locking nail versus locking plate for proximal humeral fracture fixation in an elderly patient in Misurata Medical Hospital

2025-02-02T09:37:46+00:00

Background Proximal humeral fractures (PHFs) are the third most common fracture in older patients. The purpose of the study was to prospectively evaluate the outcomes of PHF fixation with a locking blade nail (LBN) or locking plate (PHILOS) osteosynthesis in a homogeneous elderly patient population.

Methods Inclusion criteria were an age > 60 years and the capacity to give informed consent.

Patients with isolated tuberosity fractures, previous trauma or surgery, advanced osteoarthritis, fracture dislocation, pathological fractures, open fractures, neurological disorders, full-thickness rotator cuff tears, fracture line at the nail entry point or severely reduced bone quality intra-operatively were excluded.

Eighty-one patients with PHFs were randomized to treatment using LBN or PHILOS.

Outcome measures comprised Constant score, age and gender adjusted Constant score, DASH score, VAS for pain, subjective overall condition of the shoulder (1–6) and active shoulder range-of-motion in flexion and abduction. Plain radiographs were obtained in two planes. All data were collected by an independent observer at 3, 6 and 12 months postoperatively.

Results Thirteen patients were excluded intra-operatively due to rotator cuff tears, fracture morphology or poor bone-quality. Of the remaining 68 patients, 27 in the LBN and 28 in the PHILOS group completed the full follow-up.

Ambulatory Blood Pressure Monitoring Use in the Diagnosis and Management of Hypertension

2025-01-29T10:38:06+00:00

Background: The classic definition of HTN is based on office blood pressure (OBP) (CBP) measurements, yet The measurements in the office may not reflect the true BP levels. Ambulatory blood pressure measurement (ABPM) is a non- invasive method for continuous hourly monitoring of blood pressure for 24 hours during patients’ routine activities.

Objectives: to evaluate the role of ambulatory blood pressure monitoring (ABPM) in the diagnosis, to guide the accurate management of hypertension and to raise awareness of the benefit using ABPM in the reduction of cardiovascular event, stroke and end-organ damage.

Participants and methods: A cohort retrospective study of 208 patients {69 known hypertensive patients on treatment and 139 participants with high office blood pressure measurement, (OBPM)}, at Misurata primary health care clinic. They were referred by their physicians to apply ambulatory blood pressure measurement hourly for 24 hours during the period from January 2022 till June 2023. ABPM results were used to describe patients’ characteristics, different types of hypertensions, the control of the hypertensive state by treatment, and the presence of cardiovascular risk factors, were documented and analyzed.

Unstable length femur fracture in pediatric group using SBP In Misurata medical center

2025-02-02T09:21:38+00:00

Pediatric shaft femoral fractures are common injuries and account for between 1.4 to 1.7% of all fractures seen in this population.¹surgical intervention is the treatment of choice for pediatric femur fractures in patients age ≥5 years to skeletal maturity.² The surgery is dependent on many factors, such as age, fracture location, fracture pattern, and surgeon preference.³ The surgery can be more challenging for length unstable comminuted and long oblique fracture patterns. Sub muscular bridge plating restores length and alignment and rigidly stabilizes the unstable pediatric femur fracture. The technique is minimally invasive, “bridges” the fracture leaving the soft tissue intact.⁴ The technique is described here in detail.

Early and delayed Laparoscopic Cholecystectomy of Acute Cholecystitis in Department of Surgery, Faculty of Medicine, University of Misurata at period between 2018-2021

2025-02-02T09:12:11+00:00

Background: Early laparoscopic cholecystectomy has been approved as the treatment of choice for acute cholecystitis because of shorter hospital stay and no increased morbidity when compared to delayed cholecystectomy, That's why Many surgeons prefer to do early laparoscopic cholecystectomy (within 3 days from starting symptoms) for treatment of acute cholecystitis. Her in my study we will compare between early (within 72hr) and elective(after 72hr) laparoscopic cholecystectomy of acute cholecystitis in all age group (young, adult, or elderly patients).

Methods: Laparoscopic cholecystectomy was performed within 72 hours of symptoms in 84 patients (group 1) and after 72 hours in 116 patients (group 2).

The result of our study reveal relatively no difference between two groups in postoperative analgesia requirements, the rate of conversion ,or postoperative complications. But in the group 1 (early LC) had longer operating time, and shorter hospital stay. Most studies published in international literature show a statistically significant difference in the total hospital stay.