The effect of temperature on I-V characteristics and gamma rays on DNA molecule structure

Authors

  • شافية علي الدنفرية جامعة مصراتة قسم الفيزياء
  • فتحي حسن باوه جامعة مصراتة قسم الفيزياء
  • مصطفى دراه جامعة مصراتة قسم الفيزياء
  • عفاف بشير عبد الباقي جامعة مصراتة قسم الفيزياء
  • فاطمة امحمد الحوته جامعة مصراتة قسم الفيزياء
  • مروة محمد طريم جامعة مصراتة قسم الفيزياء

Keywords:

الحمض النووي, تيار كهربائي, جهد كهربائي, تلف, المقاومة النوعية

Abstract

In the first part of this research, the I-V curves of DNA were studied at two temperatures (1°C ,25°C) and the identification and detection of DNA strands. The second part of the study using the effect of CO-60 radiation on DNA. UV radiation and radioactivity calculation in time periods (from 5 minutes to 3 hours) are also studied as well.The results of the research in the first part of the study showed that the DNA is a semiconductor material in the range of V (0-3.5) at a temperature of 1ºC for a period of 5 min, and at a temperature of 25ºC the DNA showed a semiconductor behavior in the range of mv (2-0) for a period of 5 min, and at exposed for an additional 5 min, the DNA molecule showed semiconductor behavior at values ​​​​of V (0-4.5) at a temperature of 25ºC. In addition, the resistance of the molecule is affected by the two temperatures, and the breakdown of the semiconductor material occurs at a current value of no more than 200 µA and voltage values ​​of 3.5V and 4V at 0.1ºC and 25ºC respectively.Our study provides practical, important data and results to know the movement of charges and the resistance of DNA at different temperatures, as well as radiation protection and avoid damage or genetic mutations.

References

- Spielmann, H.P, Wemmer, D.E. and Jacobsen, J.P, Solution Structure of a DNA Complex With the Fluorescent Bis-Intercalator TOTO Determined by NMR Spectroscopy. Biochemistry 34, 8542-8553 (1995).

- Lindahl, T. Instability and decay of the primary structure of DNA. Nature 362, 709-715 (1993).

- Watson, J.D. and Crick, F.H.C. Molecular Structure of Nucleic Acids: A Structure for Deoxyribose Nucleic Acid. Nature 171,737-738 (1953).

- Alberts B, Johnson A, Lewis J, Raff M, Roberts K, Walter P. Molecular Biology of the Cell. 4th ed. New York: Garland Science; 2002.

- Crick, F.H.C. in Symposia of the Society for Experimental Biology, Vol. 12, Edn. 138-638 (1958).

- Crick, F. Central dogma of molecular biology. Nature 227, 561-563 (1970).

- Temin, H.M. and Mizutami, S. RNA-dependent DNA polymerase in virions of Rous sarcoma virus. Nature 226, 1211-1213 (1970).

- Mc Carthy, B.J. and Holland, J.J. Denatured DNA as a direct template for in vitro protein synthesis. Proceedings of the National Academy of Sciences 54, 880-886 (1965).

- Persson, F. and Tegenfeldt, J.O. DNA in nanochannels-directly visualizing genomic information. Chemical Society Reviews 39,985-999 (2010).64

- E N Sinurat, E Yudiarsah, I-V characteristics on G4 DNA molecule: Electric field and current dependent hopping amplitude model, IOP Conf. Series: and Engineering 578 (2019)

- Heim, Deresmes, and Vuillaume, Conductivity of DNA probed by conducting–atomic force microscopy: Effects of contact electrode, DNA structure, and surface interactions J. Appl. Phys., Vol. 96, No. 5, 1 September 2004

- Kratochvílová et al. Conductivity of natural and modified DNA measured by scanning tunneling microscopy .The effect of sequence, charge and stacking, Biophysical Chemistry 138 (2008) 3–10.

- Vengadesh Periasamy, Nastaran Rizan1, Hassan Maktuff Jaber Al-Ta’ii1,Yee Shin Tan, Hairul Annuar Tajuddin4 & Mitsumasa Iwamoto5, Measuring the Electronic Properties of DNA-Specific Schottky Diodes.Towards Detecting and Identifying Basidiomycetes DNA, Scientific RepoRts | 6:29879 | DOI: 10.1038/srep29879.

- Nadia Mahmoudi Khatir, Seyedeh Maryam Banihashemian, Vengadesh Periasamy, Wan Haliza Abd Majid, Saadah Abdul Rahman, Current-Voltage Characterization on Au-DNA-Au Junctions under the Influence of Magnetic Field, Advanced Materials Research Vols. 535-537 (2012) pp 1350-1353.

- De Yu Zang and James G. Grote, Photoelectrical effect and current-voltage characteristics in DNAmetal Schottky barriers, Proc. of SPIE Vol. 6470 64700A-1.

- J. O. Lee , K. -H. Yoo and JinheeKim, J. J. Kim, S. K. Kim, Electrical Transport Properties of DNA Molecules, Journal of the Korean Physical Society, Vol. 39, December 2001, pp. S56∼S58.

- Endres R G, Cox D L and Sing R R P 2004 Rev. Mod. Phys. 76 195-214

- Suhendro D K, Yudiarsah E and Saleh R 2010 Phys. B Phys. Condens. Matter.405 4806–4811

- Schmidt B B, Hettler M H and Schön G 2007 Phys. Rev. B 75 115125. 24

- H. W. Fink and C. Schonenberger, Nature 398, 407 (1999). 20

- D. Porath, A. Bezryadin, S. de Vries and C. Dekker, Nature 403, 635 (2000).

- D Ullien et al, The effect of the number of parallel DNA molecules on electric charge transport through ‘standing DNA, Nanotechnology 18 (2007) 424015.

- Kang D, Sun M, Zuo Z, Wang H, Lv S, Li X and Li L 2016 Phys. Lett. A 380 .977–982.

- HAYASHI, Miyoko, Satori HAYASHI, Absolute Dose Rate Measurement of Very Soft and Weak X-rays by Means of a GMcounter, JOURNAL OF RADLATION RESEARCH 5-3-4 172- 182 (Sept, Dec, 1964).

- S.W. Li, Y.S. Li, K.C. Tsui, Radioactivity in the atmosphere over Hong Kong, Journal of Environmental Radioactivity 94(2007) 98-106

Rabee B. Khader, Measure the Background Radiation in Some Parts of Nineveh Province, Rafidain journal of science, volume 21,2,p92-104,2010

- Jacob Shapiro, Radiation Protection, Third Ediation 1990, Harvard University Press, Cambridge.

- M. Hutter and T. Clark, J. Am. Chem. Soc. 118, 7574 (1996).

- Yudiarsah E, Suhendro D K and Saleh R 2014 AIP Conf. Proc. 1617 35.

Published

2024-07-07

How to Cite

الدنفرية ش. ع., باوه ف. ح., دراه م., عبد الباقي ع. ب., الحوته ف. ا., & طريم م. م. (2024). The effect of temperature on I-V characteristics and gamma rays on DNA molecule structure. Journal of Academic Research, 28(2), 39–46. Retrieved from https://lam-journal.ly/index.php/jar/article/view/684

Issue

Section

Basic Sciences