تقييم التأثير الوقائي للمستخلص المائي لقشور الرمان على السمية الكبدية المستحثة بواسطة نتريت الصوديوم في ذكور السمان

• Abd EL Khalik, D. M. T., & Omar, E. F. M. (2018). Effect of olive oil and pomegranate peels on rats suffering from chronic injury in the liver. Journal of Home Economics, 28(2).

• Abdel-Reheim, E. S., Abdel-Hafeez, H. A., Mahmoud, B. M., & Abd-Allah, E. N. (2014). Effect of food additives (monosodium glutamate and sodium nitrite) on some biochemical parameters in albino rats. International Journal of Bioassays, 3(8), 3260–3273.

• Abdel-Rahman, M. K., & Abd El-Megeid, A. A. (2006). Hepatoprotective effect of soapworts (Saponaria officinalis), pomegranate peel (Punica granatum L.) and cloves (Syzygium aromaticum Linn) on mice with ₄ hepatic intoxication. World Journal of Chemistry, 1(1), 41–46.

• Abdulmumeen, H. A., Risikat, A. N., & Sururah, A. R. (2012). Food: Its preservatives, additives and applications. International Journal of Chemical and Biochemical Sciences, 1, 36–47.

• Adewale, O. O., Samuel, E. S., Manubolu, M., & Pathakoti, K. (2019). Curcumin protects sodium nitrite-induced hepatotoxicity in Wistar rats. Toxicology Reports, 6, 1006–1011.

• Ahmadi, F., Monfared, A. L., & Shakarami, N. (2022). Protective effect of Zataria multiflora Boiss against sodium nitrite-induced hepatotoxicity in rats. Avicenna Journal of Phytomedicine, 12(3), 213–221.

• Ahmed, A. T., Belal, S. K., & Salem, A. G. (2014). Protective effect of pomegranate peel extract against diabetic induced renal histopathological changes in albino rats. IOSR Journal of Dental and Medical Sciences, 13(10), 94–105.

• Aita, N. A., & Mohammed, F. F. (2014). Effect of marjoram oil on clinicopathological, cytogenetic and histopathological alterations induced by sodium nitrite toxicity in rats. Global Veterinaria, 12, 606–616.

• Akhzari, M., Shafiee, S. M., Rashno, S., & Akmali, M. (2019). Berberine attenuated oxidative stress induced by sodium nitrite in rat liver. Jundishapur Journal of Natural Pharmaceutical Products, 14(1).

• Al-Sayeh Al-Sayeh, S., & Abu Bakr, F. (2023). Potential protective effects of olive leaf extract on sodium nitrite-induced hepatorenal toxicity (Unpublished master's thesis). Al-Zawia University.

• Al Shinnawy, M. S. (2009). Physiological effect of a food additive on some haematological and biochemical parameters of male albino rats. Egyptian Academic Journal of Biological Sciences, 2(1), 143–151.

• Alzahrani, M. S. H., & Abd Elmeged, L. S. M. (2022). Immunological and histological effects of pomegranate in hepatic rats. Pharmacophore, 13(2), 65–73.

• Amin, R. A., Elsabagh, R. A., & Amin, A. (2016). Protective effects of ascorbic acid and garlic oil against toxic effects induced by sodium nitrite as meat additive in male rats. Global Veterinaria, 16(6), 508–524.

• Bayoumi, M., & Abdel-Samie, H. (2008). Fundamentals of physiology (1st ed.). Maktabat Al-Dar Al-Arabia Lil-Kitab.

• Cerdá, B., Cerón, J. J., Tomás-Barberán, F. A., & Espín, J. C. (2003). Repeated oral administration of high doses of the pomegranate ellagitannin punicalagin to rats for 37 days is not toxic. Journal of Agricultural and Food Chemistry, 51(11), 3493–3501.

• Chidambara Murthy, K. N., Jayaprakasha, G. K., & Singh, R. P. (2002). Studies on antioxidant activity of pomegranate peel extract using in vivo models. Journal of Agricultural and Food Chemistry, 50(17), 4791–4795.

• El Mageid, M. M. A., Salama, N. A., Saleh, M. A. M., & Abo-Taleb, H. M. (2016). Evaluation of antidiabetic and hypocholesterolemic effects of pomegranate juice powders and peel powder extracts in male albino rats. IOSR Journal of Pharmacy and Biological Sciences, 11(6), 53–64.

• Faddladdeen, K. A., & Ojaimi, A. A. (2019). Protective effect of pomegranate extract against diabetic changes in adult male rat liver: Histological study. Journal of Microscopy and Ultrastructure, 7(4), 165–170.

• Hassani, M. (2022). Liver structure, function and its interrelationships with other organs: A review. International Journal of Dental and Medical Sciences Research, 4(1), 88–92.

• Hodgson, E. (2011). A textbook of modern toxicology (4th ed.). John Wiley & Sons.

• Jaiswal, V., DerMarderosian, A., & Porter, J. R. (2010). Anthocyanins and polyphenol oxidase from dried arils of pomegranate (Punica granatum L.). Food Chemistry, 118(1), 11–16.

• Juibar, F., Fattahi, H., & Sadaty, F. (2017). The effects of sodium nitrite on nitric oxide levels, serum hepatic enzymes and liver histopathology in adult male rats. Journal of Advanced Medical and Biomedical Research, 25(109), 109–119.

• Karkoubi, M. (2016). Antibacterial activity of aqueous and ethanolic extracts of sweet and sour pomegranate peels (Unpublished master's thesis). University of Martyr Hamma Lakhdar, Faculty of Exact Sciences, El Oued, Algeria.

• Khadr, A., Youssef, H., & El-Kashki, M. (2023). Utilization of pomegranate peel waste to reduce the risk of liver toxicity in rats induced by carbon tetrachloride. Journal of Home Economics, Menoufia University, 33(3), 53–66.

• Kiani, A., Yousefsani, B. S., Doroudian, P., Seydi, E., & Pourahmad, J. (2017). Mechanism of hepatotoxic effects of sodium nitrite on isolated rat hepatocytes. Toxicology and Environmental Health Sciences, 9, 244–250.

• Mahmoud, I. R., Suleiman, F. N., Hassanein, S., Mahmoud, A., et al. (2022). Effect of pomegranate peel powder on body weight, blood glucose level, and blood lipids in overweight rats. Alexandria Journal of Scientific Exchange, 43(3), 949–964.

• Manasathien, J., Indrapichate, K., & Kanok, O. I. (2012). Antioxidant activity and bioefficacy of pomegranate peel and seed extracts. Global Journal of Pharmacology, 6(2), 131–141.

• Marieb, E. (2003). Essentials of human anatomy and physiology (7th ed.). Pearson.

• Moneim, A. E. A., Dkhil, M. A., & Al-Quraishy, S. (2011). Effect of pomegranate juice and peel on liver and kidney in adult male rats. Journal of Medicinal Plants Research, 5(20), 5083–5088.

• Pathan, M. M., Khan, M. A., Somkuar, A. P., & Galkwad, N. Z. (2014). Hepatoprotective activity of Maytenus emarginata against paracetamol induced injury in male Wistar rats. International Journal of Pharmacy and Pharmaceutical Sciences, 6(8).

• Rahmani, A. H., Alsahli, M. A., & Almatroodi, S. A. (2017). Active constituents of pomegranates as potential candidates in health management. Pharmacognosy Journal, 9(5).

• Sachan, R., & Singh, R. (2023). Chemical induced liver injury: Types, mechanisms and biomarkers. Anatomical Science, 6(1).

• Salama, M. F., Abbas, A., Darweish, M. M., El-Hawwary, A. A., & Al-Gayyar, M. M. (2013). Hepatoprotective effects of cod liver oil against sodium nitrite toxicity in rats. Pharmaceutical Biology, 51(11), 1435–1443.

• Singh, B., Singh, J. P., Kaur, A., & Singh, N. (2018). Phenolic compounds as beneficial phytochemicals in pomegranate peel: A review. Food Chemistry, 261, 75–86.

• Sun, J., Aoki, K., Wang, W., Guo, A., & Misumi, J. (2006). Sodium nitrite-induced cytotoxicity in cultured human gastric epithelial cells. Toxicology in Vitro, 20(7), 1133–1138.

• Toklu, H. Z., Sehirli, O., Sener, G., Dumlu, M. U., Ercan, F., Gedik, N., & Gökmen, V. (2007). Pomegranate peel extract prevents liver fibrosis in biliary-obstructed rats. Journal of Pharmacy and Pharmacology, 59(9), 1287–1295.

• Vanisree, M., Lee, C. Y., Lo, S. F., Nalawade, S. M., Lin, C. Y., & Tsay, H. S. (2004). Production of secondary metabolites from medicinal plants by tissue cultures. Botanical Bulletin of Academia Sinica, 45(1), 1–22.

• Wei, X. L., Fang, R. T., Yang, Y. H., Bi, X. Y., Ren, G. X., Luo, A. L., & Zang, W. J. (2015). Protective effects of pomegranate peel and seed extracts on liver fibrosis induced by carbon tetrachloride in rats. BMC Complementary and Alternative Medicine, 15, 389.