Types of cervical cancer of patients attending Misturata National Cancer Institute Hospital, Libya
Keywords:
Cervical, Cancer, MisurataAbstract
Cervical cancer is one of the major public health concerns which represents the fourth most common cancer in women worldwide. Studies relating the incidence of cervical cancer with age are available in the literature, the present study was aimed at evaluating the relationship between age and cervical cancer type among women living with cervical cancer attending Misurata National Cancer Institute Hospital, Libya.
The study population included 100 female patients with age range between 20 and >70 years. Data on benign squamous, malignant squamous, benign glandular and malignant glandular were retrieved. Variables in this study were analysed using SPSS version 21.0 statistical software. The relationship between the age and cancer type was performed using Chi-square test.
Benign glandular was the most frequent cancer type recording 53 % followed by benign squamous and malignant glandular with each representing 19 % of the population. While, 9% of the population represent malignant squamous. Majority of the cervical cancer patients were within 40-49 age bracket while the least cancer incident was found among the patient between 20-29 years. No significant (p>0.05) association exist between the patients age and cancer type.
The observation in this study supports the current trend where decline in the squamous cervical cancer incidence but increase in the glandular cervical cancer were reported. Also, the disease is commonest among young women at their productive age, thus cervical cancer is a major problem in the society.
References
“C.D.C. genital HPV infection,”June 2020, https://www.cdc.gov/std/hpv/stdfact-hpv.htm.
Abate, S.M. (2015). Trends of Cervical Cancer in Ethiopia. Cervical Cancer 1: 103.
Adegoke, O., Kulasingam, S., Virnig, B. (2012). Cervical cancer trends in the United States: a 35- year population- based analysis. J. Womens Health (Larchmt) 21:1031–1037.
Al-Darwish, A., Al-Naim, A. F., Al-Mulhim, K. S., Al-Otaibi, N. K., Morsi, M. S., Aleem, A. M. (2014). “Knowledge about cervical cancer early warning signs and symptoms, risk factors and vaccination among students at a medical school in Al-Ahsa, Kingdom of Saudi Arabia. Asian Pacific Journal of Cancer Prevention. 15(6): 2529-2532
Arbyn, M., Castellsagué, X., de Sanjosé, S., Bruni, L., Saraiya, M., Bray, F., Ferlay, J. (2011). Worldwide burden of cervical cancer in 2008. Ann Oncol. 22(12):2675–86
Bhurgri, Y., Nazir K., Shaheen Y., Usman A., Faridi N., Bhurgri H., Malik, j., Bashir, j., Bhurgri, A., Kayani, N., Pervez, S., Hasan, S.H., Setna, F., Zaidi S.M.H. (2007). Patho-epidemiology of cancer cervix in Karachi. Asian Pacific Journal of Cancer Prevention 8: 357– 363.
Chan, P.K., Chang, A.R., Yu, M.Y., Li, W., Chan, M.Y., Yeung, A.C., Cheung, T.H., Yau, T.N., Wong, S.M., Yau, C.W., Ng, H.K. (2009). Age distribution of human papillomavirus infection and cervical neoplasia reflects caveat of cervical screening policies. Int. J. Cancer. 126: 297 – 301
Der, E.M., Adu- Bonsaffoh, K., Tettey, Y., Kwame-Aryee, R.A., Seffah, J.D., Alidu, H., Gyasi, R.K. (2014). Clinico-pathological characteristics of cervical cancer in Ghanian Women. Journal of Medical and Biomedical Sciences 3(3): 27-32
Distinctive features, Non-keratinizing Squamous Cell Carcinoma. Available through. https://www.bioscience.org/ref/tumpath/freprod/cervix/3/synposis.html
El Mistiri, M., Verdecchia, A., Rashid, I., El Sahli, N., El Mangush, M., Federico, M. (2007). Cancer incidence in Eastern Libya: preliminary result of the year 2003. International Journal of Cancer 120: 392 – 397.
Ferlay J, Ervik M, Lam F, Colombet M, Mery L, Piñeros M. (2020). Global cancer observatory: cancer today. Lyon, France: International Agency for Research on Cancer. https://gco.iarc.fr/today. Accessed March 15, 2021. 2020
Horst, J., Siebers, A.G., Bulten, J., Massuger, L.F., Kok, I. (2017). Increasing incidence of invasive and in situ cervical adenocarcinoma in the Netherlands during 2004–2013. Cancer Medicine; 6(2):416–423
Howlader N, Noone NA, Krapcho M (eds). SEER cancer statistics review, 1975–2012. Bethesda, MD: National Cancer Institute, 2015
HPV, Information Centre. Libya: Human Papillomavirus and Related Cancers, Fact Sheet 2021. ICO/IARC Information Centre on HPV and Cancer Libya. Accessed 02/01/2023
Irabor, G.I., Isiwele, E.M., Nnoli, M.A., Omoruyi, K.A. (2018). The Relationship between Age and Histological Types of Cervical Cancer. International Journal of Science and Research. 7(2): 260-263
Khaial, F.B., Bodalal, Z., Elramli, A., Elkhwsky, F., Eltaguri, A., Bendardaf, R. (2014) Cervical cancer in north-eastern Libya: 2000–2008, Journal of Obstetrics and Gynaecology, 34:6, 523-526
Oh, C. M., Jung, K. W., Won, Y. J., Shin, A, Kong, H. J., Jun, J. K.., Park, S.Y. (2013). Trends in the incidence of in situ and invasive cervical cancer by age group and histological type in Korea from 1993 to 2009. PLoS ONE 8: e72012.
Rose, P.G., Java, J.J., Whitney, C.W., Stehman, F.B., Lanciano, R., Thomas, G.M. (2014). Locally advanced adenocarcinoma and adenosquamous carcinomas of the cervix compared to squamous cell carcinomas of the cervix in gynecologic oncology group trials of cisplatin-based chemoradiation. Gynecol Oncol. 135:208–12.
Rositch, A.F., Levinson, K., Suneja, G., Monterosso, A., Schymura, M.J., McNeel, T.S., Horner, M., Engels, E., Shiels, M.S. (2022). Epidemiology of Cervical Adenocarcinoma and Squamous Cell Carcinoma Among Women Living With Human Immunodeficiency Virus Compared With the General Population in the United States. Clinical Infectious Diseases. 74(5):814–20
Shanmugham, D., Vijay A, Rangaswamy T. (2014). Colposcopic evaluation of patient with persistant inflammatory pap smear. Sch J Appl Med Sci. 2: 1010‑101
Shrestha AD, Neupane D, Vedsted P, Kallestrup P. (2018). Cervical cancer prevalence, incidence and mortality in low and middle income countries: A systematic review. Asian Pac J Cancer Prev. 19:319‑24
Sule, S.T., Shehu, M.S. (2007). Cervical cancer management in Zaria, Nigeria. African Journal of Health Sciences 14: 149-153
Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I., Jemal A, Bray F. (2021). Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin; 71:209‑49.
Tornesello, M.L., Losito, S., Benincasa G., Fulciniti F., Botti, G., Greggi, S., Buonaguro, L., Buonaguro, F.M. (2011). Human papillomavirus (HPV) genotypes and HPV16 variants and risk of adenocarcinoma and squamous cell carcinoma of the cervix. Gynecol Oncol. 121:32–42.
WHO,“Human papillomavirus (HPV) and cervical cancer,”June 2020, https://www.who.int/news-room/fact-sheets/detail/human-papillomavirus-(hpv)-and-cervical-cancer.
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Copyright (c) 2023 AI Abudabbus، NJ Elmahaishi، JA Badmus، PI Adegbola
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